Eli Zaretskii has announced that he expects to merge the new native compilation code into the Master branch next week. This is a significant milestone for a really important feature.
Most of the comments were along the lines of “I’ve been using this feature for months and haven’t had any problems.” A few expressed concerns about some edge cases but I didn’t see any show stoppers. The largest TODO appears to be documentation.
Once it gets merged into Master, we can reasonably expect that it will officially be released with Emacs 28. Perhaps—we can only hope—native compilation will put an end to the “Emacs is slow” snark. But probably not.