There are, I suppose, a few Lisp programmers using Emacs who resist paredit but most of the rest of us have long since succumbed to its charms. It can be a bit difficult to get used to but once you do, it’s a tool you don’t want to live without.
There is a problem though. Since Paredit’s introduction 20 years ago, Emacs has added new default keybindings some of which conflict with the existing Paredit keybindings. I can remember having to remap some of Paredit’s keybindings to avoid this.
Bozhidar Batsov has a nice post that discusses these conflicts and how to deal with them. My use of Paredit is mostly restricted to a small subset of its commands so I haven’t experienced the full impact of these conflicts. Even for those commands I do use—like slurp and barf—the conflict doesn’t bother me because I never use the arrow keys to move the cursor.
If you use more of the Paredit commands, take a look at Batsov’s post for his suggestions for resolving them. Or, you could switch to Fuco1’s smartparens, which avoids these conflicts while providing the same functionality and extending it to other file types.
One thing for sure, if you use paredit-splice-sexp you’ll want to resolve its conflict because Emacs uses Meta+s as the search map prefix and that is too useful to forego.
In any event if you’re a Paredit or Smartparens user, you should definitely take a look at Batsov’s post.