Gregory Stein over at Caches to Caches has a really nice tutorial on configuring mu4e and offlineimap to handle your email from within Emacs. That’s an on-going project—delayed mostly by laziness—here at Irreal so I was especially interested in the post. My only complaint is the use of offlineimap instead of the faster mbsync.
Still, Stein shows you how to get things set up so that your mail is automatically downloaded every 5 minutes and Emacs lets you know when you have email. He found a couple little glitches when he was configuring his system and he explains those and gives workarounds for them.
If you’ve been looking for a way to move email inside Emacs, mu4e is an excellent solution. If you want some inspiration, take a look at my post where I discuss Ben Maughan’s email setup. As I say in that post, Maughan has leveraged mu4e to make what I consider a near-perfect email setup.