Sacha Chua has another Emacs chat up. This time it's with Jānis Mancēviĉs. It's a far ranging talk but one of the interesting aspects is Mancēviĉs's use of Org mode for Literate Programming. He and his team mate use Org to pass around their code and documentation and then tangle the code for compilation. Mancēviĉs talks a bit about the benefits of Literate Programming and why they use it even though the up-front costs are a little greater. My impression is that he uses the Literate Programming paradigm not so much to produce finished documentation à la Knuth but to keep information about the algorithms and functions together with the code.
Another nice strategy that Mancēviĉs uses is cold folding. I used to use that occasionally with Vim but forgot about it when I moved to Emacs. Org mode has built-in folding, of course, but the more general Emacs folding can useful in non-Org files such as your .emacs, programming source, or text files.
The video is a little over an hour so plan accordingly. As with all of Chua's Emacs chats, you're apt to learn a thing or two so it will be worth your time.